Having been drawn to face each other in the FA Cup fifth round, Manchester City host Newcastle United at the Etihad Stadium on Saturday (20:00 GMT) hoping to narrow the five-point gap between themselves and league leaders Arsenal.
The clubs have already played each other in a two-legged League Cup semi-final and could potentially meet again in the last four of the Champions League, leading to some cries of fatigue from their supporters.
Pep Guardiola's focus, however, will be solely on avenging a 2-1 reverse at St James' Park in November and using this game in hand to shrink the Gunners' lead to two points.
Citizens cane Magpies
City boast a frankly ridiculous home record against the Magpies. They are unbeaten in 21 and have won each of their past 16 meetings in Eastlands, the second longest home winning streak against an opponent in English top-flight history, after Everton's 22 consecutive wins over Fulham from 1961 to 2018.
The last six of those home wins over Newcastle have come without conceding a goal. Injuries have left City weak in central defence at times this season, but in attack they continue to possess an embarrassment of riches.
Amid increased competition for his place in the starting XI, homegrown hero Phil Foden is approaching a significant milestone. His next Premier League goal involvement will be his 100th for the club, an achievement unlocked by just five City players to date.
Toon's top-half travel troubles
Newcastle come into the game off the back of three straight wins in all competitions, but their league form has been far from good, with last week's 2-1 success at Tottenham Hotspur their first win in five attempts.
That result moved Eddie Howe's side 10th in the table but the Magpies' away record against teams starting the day in the top half is not an encouraging one for the travelling Toon Army; they're winless in 10 against such opposition, losing seven of those. Against teams in the top two, that record stretches to no wins in 37.
Harvey Barnes' impressive performances this season sparked rumours of a potential switch of international allegiance ahead of this summer's World Cup, although Scotland head coach Steve Clarke recently confirmed that the winger is concentrating on adding to his one England cap.
Having bagged a brace earlier in the season, Barnes is aiming to become the first Newcastle player to score home and away against City in the same league season since Alan Shearer in 2004-05.
Barnes and co will be aiming to fire Newcastle to their first top-flight league double over Manchester City since 1955-56. However, the omens are not good; they've played 20 Premier League games at the Etihad without a victory (drawn two, lost 18), the most any team has played at a stadium without winning in the competition's history.