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Ohio State vs Michigan State Prediction, Picks & Odds for Today's College Basketball Game

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No. 15 Michigan State is trying to snap out of a rare late-season slump before March begins, while Ohio State looks to get its first Quad 1 win of the season to get on the positive side of the tournament bubble today.

My Ohio State vs. Michigan State predictions and college basketball picks trust Michigan State more than Ohio State, so look for Sparty to get the cover on Sunday, February 22.

Ohio State vs Michigan State prediction

Ohio State vs Michigan State best bet: Michigan State -10.5 (-116)

The Michigan State Spartans believe the ship is righted after an 82-59 win over UCLA. The Spartans showed every sign they're past a five-game slump that saw them trail at the half of every game, losing three outright.

The Spartans had their best D in a month and shot better than they have in two straight.

The Ohio State Buckeyes have been a different team against Quad 1 foes. They're shooting 48.5% from two and 31.9% from three, compared to 62.7% and 36.3% against everyone else. The defense is 70 points worse against twos and 30 worse against threes.

Ohio State vs Michigan State same-game parlay

Both teams rank in the 200s, nationally, in pace. Michigan State has been Over the last six games, but the Spartans haven’t been playing the defense they want over most of that stretch. Ohio State has been Under in four of the last five.

Jordan Scott has seen his role increase lately. He’s averaging 7.8 shots, 28.8 minutes, and 11.4 points in the last five games, up from 3.7 shots, 16.5 minutes, and 4.5 points prior to that.

Ohio State vs Michigan State SGP

  • Michigan State -10.5
  • Under 146
  • Jordan Scott Over 9.5 points

Our beyond the arc SGP: Fears finds open men

If Michigan State is playing the way coach Tom Izzo wants, they’ll be sharing the ball and taking good shots. Jeremy Fears has double-digit assists in the last four games and is averaging 9.3 on the season.

Jaxon Kohler has made multiple 3-pointers in two of the last three games. Just as importantly, he’s taken 20 threes over that stretch. If he keeps shooting, they’ll go in.

Ohio State vs Michigan State SGP

  • Under 146
  • Jordan Scott Over 9.5 points
  • Jeremy Fears Over 8.5 assists
  • Jaxon Kohler Over 1.5 3-pointers

Ohio State vs Michigan State odds

  • Spread: Ohio State +10.5 | Michigan State -10.5
  • Moneyline: Ohio State +460 | Michigan State -670
  • Over/Under: Over 146.5 | Under 146.5 

Ohio State vs Michigan State betting trend to know

Michigan State has hit the Moneyline in 14 of their last 16 games at home. Find more college basketball betting trends for Ohio State vs. Michigan State.

How to watch Ohio State vs Michigan State

LocationBreslin Center, East Lansing, MI
DateSunday, February 22, 2026
Tip-off1:00 p.m. ET
TVCBS

Ohio State vs Michigan State key injuries

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
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